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Compile Data Set for Download or QSAR

Found 4 hits of ic50 data for polymerid = 49000306,50007499   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-2


(Homo sapiens)
BDBM50101971
PNG
(BAY-E-9736 | CHEBI:7575 | Nimodipine | Nimotop)
Show SMILES COCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C |c:7,12|
Show InChI InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
PDB

UniProtKB/SwissProt

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DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 30n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.2c00458
BindingDB Entry DOI: 10.7270/Q2ZP4B6J
More data for this
Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit beta-2


(Homo sapiens)
BDBM50602415
PNG
(CHEMBL5190568)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cc(ccc1C)C(=O)NCc1ccc(C)nc1
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MCE
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.2c01208
BindingDB Entry DOI: 10.7270/Q2MC943D
More data for this
Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit beta-2


(Homo sapiens)
BDBM50573712
PNG
(CHEBI:66722 | CHEMBL71260)
Show SMILES CCCCCCC\C=C/CC#CC#C[C@H](O)C=C
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.13E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human alpha1c/beta2a/alpha2delta1 Cav1.2 expressed in HEK293 cells assessed as time course of inhibition of membrane potential measured...


Citation and Details

Article DOI: 10.1021/acs.jnatprod.1c00136
BindingDB Entry DOI: 10.7270/Q2HD80GQ
More data for this
Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit beta-2


(Homo sapiens)
BDBM50573711
PNG
(CHEMBL4874732)
Show SMILES [#6]-[#6](-[#6])[Si;v4](C#CC#C[#6@H](-[#8])-c1ccccc1)([#6](-[#6])-[#6])[#6](-[#6])-[#6] |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.73E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human alpha1c/beta2a/alpha2delta1 Cav1.2 expressed in HEK293 cells assessed as time course of inhibition of membrane potential measured...


Citation and Details

Article DOI: 10.1021/acs.jnatprod.1c00136
BindingDB Entry DOI: 10.7270/Q2HD80GQ
More data for this
Ligand-Target Pair